U46619
From Infogalactic: the planetary knowledge core
(Redirected from U-46619)
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| Names | |
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| IUPAC name
(Z)-7-[(1S,4R,5R,6S)-5-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid
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| Identifiers | |
56985-40-1  |
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| ChEMBL | ChEMBL357834  |
| 1888 | |
| Jmol 3D model | Interactive image |
| PubChem | 5311493 |
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| Properties | |
| C21H34O4 | |
| Molar mass | 350.49 g/mol |
| Vapor pressure | {{{value}}} |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is ?) |
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| Infobox references | |
U46619 is a stable synthetic analog of the endoperoxide prostaglandin PGH2 first prepared in 1975,[1] and acts as a thromboxane A2 (TP) receptor agonist.[2] It potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations.[3] and exhibits many properties similar to thromboxane A2, including shape change and aggregation of platelets [4] and smooth muscle contraction. U46619 is a vasoconstrictor that mimics the hydroosmotic effect of vasopressin.[5]
References
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