Prostaglandin E synthase (or PGE synthase) is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E (PGE) from prostaglandin H2.[2][3]
The synthase generating PGE2 is a membrane-associated protein.
Biosynthesis of eicosanoids.
Isozymes
Humans express three prostaglandin-E synthase isozymes, each encoded by a separate gene:
References
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