Melitracen

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Melitracen
Skeletal formula of melitracen
Ball-and-stick model of the melitracen molecule
Systematic (IUPAC) name
3-(10,10-dimethylanthracen-9(10H)-ylidene)-N,N-dimethylpropan-1-amine
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
  • ℞ (Prescription only)
Routes of
administration		 Oral, IM
Identifiers
CAS Number 5118-29-6 N
ATC code N06AA14 (WHO)
PubChem CID: 25382
ChemSpider 23697 YesY
UNII Q7T0Y1109Z YesY
KEGG D08171 YesY
ChEMBL CHEMBL110094 YesY
Chemical data
Formula C21H25N
Molecular mass 291.43 g/mol
  • c3ccc2c(/C(c1c(cccc1)C2(C)C)=C/CCN(C)C)c3
  • InChI=1S/C21H25N/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21/h5-8,10-14H,9,15H2,1-4H3 YesY
  • Key:GWWLWDURRGNSRS-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Melitracen (Adaptol, Dixeran, Melixeran, Thymeol, Trausabun) is a tricyclic antidepressant (TCA) marketed in Europe and Japan by Lundbeck and Takeda, respectively, for the treatment of depression and anxiety.[1][2][3][4] In addition to single drug preparations, it is also available as Deanxit, a combination product containing both melitracen and flupentixol.[5][6][7][8]

The pharmacology of melitracen has not been properly investigated and is largely unknown, but it is likely to act in a similar manner to other TCAs. Indeed, melitracen is reported to have imipramine and amitriptyline-like effects and efficacy against depression and anxiety, though with improved tolerability and a somewhat faster onset of action.[9][10]

See also

References

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