TC-1827

TC-1827

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Names
IUPAC name (S)-N-Methyl-5-(5-pyrimidinyl)-4-penten-2-amine
Identifiers
CAS Number	547741-76-4 Y
Jmol 3D model	Interactive image
SMILES C[C@H](NC)C/C=C/C1=CN=CN=C1
Properties
Chemical formula	C10H15N3
Molar mass	177.25 g·mol−1
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

TC-1827 is an orally active, selective agonist of the α₄β₂ nicotinic receptors. Administration of TC-1827 improved memory and learning in a variety in rodents, and increased long-term potentiation in hippocampal slices. In addition, the compound was without significant cardiovascular side effects, except for a small, transient rise in arterial blood pressure. The pro-cognitive effects of TC-1827 last much longer than the short half life (0.2 - 1.0 hours) would suggest.