Histamine receptor

From Infogalactic: the planetary knowledge core
(Redirected from Histamine receptors)
Jump to: navigation, search

The histamine receptors are a class of G protein–coupled receptors with histamine as their endogenous ligand.[1]

There are four known histamine receptors:

Comparison

Histamine receptors
Receptor Mechanism Function Antagonists
H1 Gq
H2 Gs
Ca2+
H3 Gi
H4 Gi

There are several splice variants of H3 present in various species. Though all of the receptors are 7-transmembrane g protein coupled receptors, H1 and H2 are quite different from H3 and H4 in their activities. H1 causes an increase in PIP2 hydrolysis, H2 stimulates gastric acid secretion, and H3 mediates feedback inhibition of histamine.

References

  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. Lua error in package.lua at line 80: module 'strict' not found.

External links