GPR143
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Ocular albinism type 1 protein | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
Symbol | Ocular_alb | ||||||||
Pfam | PF02101 | ||||||||
Pfam clan | CL0192 | ||||||||
InterPro | IPR001414 | ||||||||
|
G-protein coupled receptor 143 is a protein encoded by the GPR143 gene in humans.[1][2][3]
Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes.[3]
The GPR143 gene is regulated by the Microphthalmia-associated transcription factor.[4][5]
L-DOPA is an endogenous ligand for OA1.[6]
Interactions
GPR143 has been shown to interact with GNAI1.[2]
References
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Further reading
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External links
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