GNB5
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Guanine nucleotide-binding protein subunit beta-5 is a protein that in humans is encoded by the GNB5 gene.[1] Alternatively spliced transcript variants encoding different isoforms exist.[2]
Function
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.[2]
GNB5 has been shown to differentially control RGS protein stability and membrane anchor binding, and therefore is involved in the control of complex neuronal G protein signaling pathways.[3]
Interactions
GNB5 has been shown to interact with:
References
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Further reading
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