GNA11

Guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Identifiers
Symbols	GNA11 ; FBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2
External IDs	OMIM: 139313 MGI: 95766 HomoloGene: 20474 GeneCards: GNA11 Gene
Gene ontology Molecular function • GTPase activity • signal transducer activity • GTP binding • G-protein beta/gamma-subunit complex binding • type 2A serotonin receptor binding • metal ion binding Cellular component • photoreceptor outer segment • cytoplasm • lysosomal membrane • heterotrimeric G-protein complex • plasma membrane • extracellular exosome Biological process • skeletal system development • action potential • signal transduction • adenylate cyclase-modulating G-protein coupled receptor signaling pathway • G-protein coupled acetylcholine receptor signaling pathway • heart development • blood coagulation • phototransduction, visible light • metabolic process • entrainment of circadian clock • platelet activation • regulation of melanocyte differentiation • developmental pigmentation • phospholipase C-activating dopamine receptor signaling pathway • cellular response to pH Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2767	14672
Ensembl	ENSG00000088256	ENSMUSG00000034781
UniProt	P29992	P21278
RefSeq (mRNA)	NM_002067	NM_010301
RefSeq (protein)	NP_002058	NP_034431
Location (UCSC)	Chr 19: 3.09 – 3.12 Mb	Chr 10: 81.53 – 81.55 Mb
PubMed search	[1]	[2]

Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene. Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.

See also

• Gq alpha subunit