LY-235,959

From Infogalactic: the planetary knowledge core
Jump to: navigation, search
LY-235,959
240px
Systematic (IUPAC) name
(3S,4aR,6S,8aR)-6-(phosphonomethyl)-1,2,3,4,4a,5,6,7,8, 8a-decahydroisoquinoline-3-carboxylic acid
Identifiers
CAS Number 137433-06-8 YesY
PubChem CID: 131938
ChemSpider 116555
Chemical data
Formula C11H20NO5P
Molecular mass 277.11 g/mol
  • [H][C@]12[C@](CC[C@H](CP(O)(O)=O)C2)([H])CN[C@H](C(O)=O)C1
  • InChI=1S/C11H20NO5P/c13-11(14)10-4-9-3-7(6-18(15,16)17)1-2-8(9)5-12-10/h7-10,12H,1-6H2,(H,13,14)(H2,15,16,17)/t7-,8-,9+,10-/m0/s1
  • Key:STIRHCNEGQQBOY-QEYWKRMJSA-N

LY-235,959 is a competitive antagonist at the NMDA receptor.[1] It has analgesic and neuroprotective effects and causes hypothermia in animal models,[2] as well as reducing the development of tolerance to morphine and altering the reinforcing effects of cocaine.[3][4][5][6][7]

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  7. ↑ Lua error in package.lua at line 80: module 'strict' not found.


Retrieved from "https://infogalactic.com/w/index.php?title=LY-235,959&oldid=713215763"