FUBIMINA

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FUBIMINA
FUBIMINA structure.png
Systematic (IUPAC) name
(1-(5-fluoropentyl)-1H-benzo[d]imidazol-2-yl)(naphthalen-1-yl)methanone
Clinical data
Legal status
Identifiers
ChemSpider 30646758
Chemical data
Formula C23H21FN2O
Molecular mass 360.4 g/mol
  • O=C(C1=NC2=C(C=CC=C2)N1CCCCCF)C3=CC=CC4=CC=CC=C43
  • InChI=1S/C23H21FN2O/c24-15-6-1-7-16-26-21-14-5-4-13-20(21)25-23(26)22(27)19-12-8-10-17-9-2-3-11-18(17)19/h2-5,8-14H,1,6-7,15-16H2
  • Key:KUESSZMROAFKQJ-UHFFFAOYSA-N

FUBIMINA (also known as BIM-2201, BZ-2201 and FTHJ) is a synthetic cannabinoid that is the benzimidazole analog of AM-2201[1] and has been used as an active ingredient in synthetic cannabis products.[2] It was first identified in Japan in 2013, alongside MEPIRAPIM.[3]

FUBIMINA acts as a reasonably potent agonist for the CB2 receptor (Ki = 23.45 nM), with 12x selectivity over CB1 (Ki = 296.1 nM), and does not fully substitute for Δ9-THC in rat discrimination studies.[4]

Related benzimidazole derivatives have been reported to be highly selective agonists for the CB2 receptor.[5]

See also

References

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