Zofenopril

Zofenopril

250px
Systematic (IUPAC) name
(2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
Identifiers
CAS Number	81872-10-8 Y
ATC code	C09AA15 (WHO)
PubChem	CID: 92400
IUPHAR/BPS	6462
ChemSpider	83422 N
UNII	290ZY759PI N
KEGG	D08688 Y
ChEBI	CHEBI:78539 N
ChEMBL	CHEMBL331378 N
Chemical data
Formula	C22H23NO4S2
Molecular mass	429.552 g/mol
SMILES O=C(N2[C@H](C(=O)O)C[C@H](Sc1ccccc1)C2)[C@H](C)CSC(=O)c3ccccc3
InChI InChI=1S/C22H23NO4S2/c1-15(14-28-22(27)16-8-4-2-5-9-16)20(24)23-13-18(12-19(23)21(25)26)29-17-10-6-3-7-11-17/h2-11,15,18-19H,12-14H2,1H3,(H,25,26)/t15-,18+,19+/m1/s1 N Key:IAIDUHCBNLFXEF-MNEFBYGVSA-N N
NY (what is this?)  (verify)

Zofenopril (also known as zofenoprilum [Latin]) is an angiotensin converting enzyme (ACE) inhibitor with cardioprotective properties indicated for the treatment of hypertension.

In small studies, zofenopril appeared significantly more effective than the older antihypertensives atenolol and enalapril, and was associated with fewer adverse effects.

File:Zofenoprilat structure.svg

Zofenoprilat — the active metabolite of zofenopril