VPS24
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Charged multivesicular body protein 3 is a protein that in humans is encoded by the VPS24 gene.[1][2][3]
Function
This gene encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants encoding different isoforms.[3]
Interactions
VPS24 has been shown to interact with IGFBP7.[1]
References
Further reading
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