Tyloxapol
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| Systematic (IUPAC) name | |
|---|---|
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formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
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| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Identifiers | |
| CAS Number | 25301-02-4  |
| ATC code | R05CA01 (WHO) |
| PubChem | CID: 71388 |
| DrugBank | DB06439  |
| ChemSpider | 11052515 |
| UNII | Y27PUL9H56 |
| KEGG | D03261 |
| ChEMBL | CHEMBL1201548 |
| Chemical data | |
| Formula | (C15H21O(C2H4O)m)n |
| Molecular mass | variable |
| (what is this?) (verify) |
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Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent[citation needed] (containing mucus and pus) bronchopulmonary secretions,[1][2] administered by inhalation through a nebulizer[3] or with a stream of oxygen.
With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.[4]
Tyloxapol is the main active ingredient of the medical device Tacholiquin®. Tacholiquin® is an expectorant designated for inhalation and instillation reaching the upper and lower airways. Other brand names of pharmaceutical products containing Tyloxpol are Exosurf and Alevaire.
References
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- ↑ Drugs.com: Tyloxapol definition
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