Template:PBB/1440

Colony stimulating factor 3 (granulocyte)
Ribbon diagram showing three molecules of human G-CSF. From PDB: 1rhg​
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1CD9, 1GNC, 1PGR, 1RHG, 2D9Q
Identifiers
Symbols	CSF3 ; C17orf33; CSF3OS; GCSF
External IDs	OMIM: 138970 MGI: 1339751 HomoloGene: 7677 GeneCards: CSF3 Gene
Gene ontology Molecular function • cytokine activity • granulocyte colony-stimulating factor receptor binding • growth factor activity • enzyme binding Cellular component • extracellular space Biological process • immune response • multicellular organismal development • positive regulation of cell proliferation • positive regulation of phosphatidylinositol 3-kinase signaling • cytokine-mediated signaling pathway • positive regulation of actin filament polymerization • granulocyte differentiation • positive regulation of protein binding • positive regulation of peptidyl-serine phosphorylation • positive regulation of transcription factor import into nucleus • positive regulation of myeloid cell differentiation • positive regulation of transcription from RNA polymerase II promoter • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of protein kinase B signaling • cellular response to lipopolysaccharide • cellular response to cytokine stimulus • negative regulation of neuron death • positive regulation of actin cytoskeleton reorganization Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1440	12985
Ensembl	ENSG00000108342	ENSMUSG00000038067
UniProt	P09919	P09920
RefSeq (mRNA)	NM_000759	NM_009971
RefSeq (protein)	NP_000750	NP_034101
Location (UCSC)	Chr 17: 40.02 – 40.02 Mb	Chr 11: 98.7 – 98.7 Mb
PubMed search	[1]	[2]