TRIP6
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Thyroid receptor-interacting protein 6 is a protein that in humans is encoded by the TRIP6 gene.[1][2][3]
Function
This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.[3]
Interactions
TRIP6 has been shown to interact with LPAR2,[4] BCAR1[4][5] and HOXA9.[6]
References
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