Statine

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Statine
Statine skeletal.svg
Names
IUPAC name
(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid
Identifiers
49642-07-1
Abbreviations AHMHA, Sta
ChEBI CHEBI:45769
ChemSpider 110446
Jmol 3D model Interactive image
PubChem 123915
  • InChI=1S/C8H17NO3/c1-5(2)3-6(9)7(10)4-8(11)12/h5-7,10H,3-4,9H2,1-2H3,(H,11,12)/t6-,7-/m0/s1
    Key: DFVFTMTWCUHJBL-BQBZGAKWSA-N
  • N[C@@H](CC(C)C)[C@@H](O)CC(O)=O
Properties
C8H17NO3
Molar mass 175.23 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Statine is a gamma amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases.[1] It is thought to be responsible for the inhibitory activity of pepstatin because it mimics the tetrahedral transition state of peptide catalysis.[2]

References

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  2. Lua error in package.lua at line 80: module 'strict' not found.


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