RAD54B
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.[1][2][3]
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.[3]
Interactions
RAD54B has been shown to interact with RAD51.[2]
References
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