Methylpiperidinopyrazole

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Methylpiperidinopyrazole
Methylpiperidinopyrazole.svg
Systematic (IUPAC) name
4-[2-(4-hydroxyphenyl)-4-methyl-3-[4-(2-piperidin-1-ylethoxy)phenyl]-1H-pyrazol-5-ylidene]cyclohexa-2,5-dien-1-one
Identifiers
CAS Number 289726-02-9
PubChem CID: 6604927
ChemSpider 5037183
Chemical data
Formula C29H31N3O3
Molecular mass 469.57474 g/mol
  • CC1=C(N(NC1=C2C=CC(=O)C=C2)C3=CC=C(C=C3)O)C4=CC=C(C=C4)OCCN5CCCCC5
  • InChI=1S/C29H31N3O3/c1-21-28(22-5-11-25(33)12-6-22)30-32(24-9-13-26(34)14-10-24)29(21)23-7-15-27(16-8-23)35-20-19-31-17-3-2-4-18-31/h5-16,30,34H,2-4,17-20H2,1H3
  • Key:PFTIONINVMINHE-UHFFFAOYSA-N

Methylpiperidinopyrazole (MPP) is a synthetic, non-steroidal, and highly selective antagonist of ERα that is used in scientific research to study the function of this receptor.[1][2][3] It has 200-fold selectivity for ERα over ERβ and 1000-fold selectivity for blocking ERα-mediated gene transcription relative to that of ERβ.[4]

See also

References

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  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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