Lymphangitis carcinomatosa
| Classification and external resources | |
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| DiseasesDB | 7672 |
| Patient UK | [1] |
Lymphangitis carcinomatosa is inflammation of the lymph vessels (lymphangitis) caused by a malignancy. Breast, lung, stomach, pancreas, and prostate cancers are the most common tumors that result in lymphangitis. Lymphangitis carcinomatosa was first described by pathologist Gabriel Andral in 1829 in a patient with uterine cancer.
Lymphangitis carcinomatosis most often affects people 40–49 years of age.[1]
Pathology
In most cases, lymphangitis carcinomatosis is caused by the dissemination of a tumor with its cells along the lymphatics.[2] However, in about 20 percent of cases, the inflammation of the lymphatic tubules (lymphangitis) is caused by a tumor that blocks the drainage of the lymph duct. In the lung, this is often caused by a centrally located mass, near the hilum of the lung that blocks lymphatic drainage.
Prognosis
Previously, the finding of lymphangitis carcinomatosis meant about a six-month life expectancy.[2] However, improved treatment has improved survival in patients with lymphangitis carcinomatosis, with patients often surviving three or more years with treatment.[2]
History
Lymphangitis carcinomatosa was first described by pathologist Gabriel Andral in 1829 in a patient with uterine cancer.[3]
See also
References
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