Luzindole
From Infogalactic: the planetary knowledge core
File:Luzindole.svg | |
Systematic (IUPAC) name | |
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N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
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Clinical data | |
Legal status |
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Identifiers | |
CAS Number | 117946-91-5 |
ATC code | None |
PubChem | CID: 122162 |
ChemSpider | 108959 |
ChEBI | CHEBI:131788 ![]() |
Chemical data | |
Formula | C19H20N2O |
Molecular mass | 292.375 g/mol |
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Luzindole (N-0774), (N-acetyl-2-benzyltryptamine), is a drug used in scientific research to study the role of melatonin in the body. Luzindole acts as a selective melatonin receptor antagonist,[1] with approximately 11- to 25-fold greater affinity for the MT2 over the MT1 receptor.[2][3] In animal studies, it has been observed to disrupt the circadian rhythm as well as produce antidepressant effects.[2][4]
References
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- Acetamides
- Indoles
- Tryptamines
- Melatonin receptor antagonists