HIST1H3J

Histone cluster 1, H3j
250px PDB rendering based on 1aoi.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1CS9, 1CT6, 1O9S, 1Q3L, 2B2T, 2B2U, 2B2V, 2B2W, 2C1J, 2C1N, 2CV5, 2KWJ, 2KWK, 2L75, 2LBM, 2M0O, 2OQ6, 2OT7, 2OX0, 2RI7, 2UXN, 2VPG, 3A1B, 3AFA, 3AVR, 3AYW, 3AZE, 3AZF, 3AZG, 3AZH, 3AZI, 3AZJ, 3AZK, 3AZL, 3AZM, 3AZN, 3B95, 3KMT, 3KQI, 3LQI, 3LQJ, 3O34, 3O35, 3O37, 3QJ6, 3RIG, 3RIY, 3SOU, 3SOW, 3U31, 3U3D, 3U4S, 3U5N, 3U5O, 3U5P, 3UEE, 3UEF, 3UIG, 3UII, 3UIK, 3V43, 3W96, 3W97, 3W98, 3W99, 3WA9, 3WAA, 3WKJ, 3ZG6, 3ZVY, 4A0J, 4A0N, 4A7J, 4BD3, 4C1Q, 4F4U, 4F56, 4FWF, 4HON, 4I51, 4L7X, 4LK9, 4LKA, 4LLB, 4LXL, 4N4H, 4UP0, 4UY4, 4Z0R
Identifiers
Symbols	HIST1H3J ; H3/j; H3FJ
External IDs	OMIM: 602817 HomoloGene: 134479 GeneCards: HIST1H3J Gene
Gene ontology Molecular function • DNA binding • protein binding • histone binding • protein heterodimerization activity Cellular component • nuclear chromosome • nucleosome • nuclear nucleosome • extracellular region • nucleus • nucleoplasm • membrane • protein complex • extracellular exosome Biological process • chromatin silencing at rDNA • positive regulation of defense response to virus by host • chromatin organization • nucleosome assembly • DNA replication-dependent nucleosome assembly • small GTPase mediated signal transduction • blood coagulation • gene expression • DNA methylation on cytosine • regulation of gene expression, epigenetic • negative regulation of gene expression, epigenetic • protein heterotetramerization • regulation of gene silencing Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8356	97908
Ensembl	ENSG00000197153	ENSMUSG00000099517
UniProt	P68431	P68433
RefSeq (mRNA)	NM_003535	NM_145073
RefSeq (protein)	NP_003526	NP_659539
Location (UCSC)	Chr 6: 27.89 – 27.89 Mb	Chr 13: 23.54 – 23.54 Mb
PubMed search	[1]	[2]

Histone H3.1 is a protein that in humans is encoded by the HIST1H3J gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.