Goblet cell carcinoid
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| Goblet cell carcinoid | |
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| File:Goblet cell carcinoid -2- high mag.jpg
Micrograph showing a goblet cell carcinoid. H&E stain.
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| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| Patient UK | Goblet cell carcinoid |
The goblet cell carcinoid, abbreviated GCC and also known as crypt cell carcinoma and neuroendocrine tumour with goblet cell differentiation, is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.[1]
Sign and symptoms
GCCs may present as appendicitis.
Diagnosis
File:Goblet cell carcinoid - very low mag.jpg
Micrograph of a goblet cell carcinoid. H&E stain.
GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).
Prognosis
GCCs have an aggressive course vis-a-vis other appendiceal neuroendocrine tumours.[1]
Treatment
GCCs are treated with surgery.
See also
References
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Wikimedia Commons has media related to Goblet cell carcinoid. |
