GGTL3

Gamma-glutamyltransferase 7
Identifiers
Symbols	GGT7 ; D20S101; GGT4; GGTL3; GGTL5; dJ18C9.2
External IDs	OMIM: 612342 MGI: 1913385 HomoloGene: 70866 GeneCards: GGT7 Gene
EC number	2.3.2.2, 3.4.19.13
Gene ontology Molecular function • gamma-glutamyltransferase activity • protein binding • glutathione hydrolase activity Cellular component • integral component of membrane • anchored component of external side of plasma membrane Biological process • proteolysis • glutathione metabolic process • glutathione biosynthetic process • leukotriene biosynthetic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2686	207182
Ensembl	ENSG00000131067	ENSMUSG00000027603
UniProt	Q9UJ14	Q99JP7
RefSeq (mRNA)	NM_178026	NM_144786
RefSeq (protein)	NP_821158	NP_659035
Location (UCSC)	Chr 20: 34.84 – 34.87 Mb	Chr 2: 155.49 – 155.52 Mb
PubMed search	[1]	[2]

Gamma-glutamyltransferase 7 is an enzyme that in humans is encoded by the GGT7 gene.

Gamma-glutamyltransferase is a membrane-associated protein involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene is similar in sequence to gamma-glutamyltransferase, but its function is unknown.