GABRQ

Gamma-aminobutyric acid (GABA) A receptor, theta
Identifiers
Symbols	GABRQ ; THETA
External IDs	OMIM: 300349 MGI: 1888498 HomoloGene: 10233 IUPHAR: 418 ChEMBL: 2843 GeneCards: GABRQ Gene
Gene ontology Molecular function • transmembrane signaling receptor activity • GABA-A receptor activity • extracellular ligand-gated ion channel activity • chloride channel activity • neurotransmitter transporter activity Cellular component • plasma membrane • integral component of plasma membrane • cell junction • chloride channel complex • neuron projection • receptor complex • synapse • postsynaptic membrane • GABA-A receptor complex Biological process • neurotransmitter transport • signal transduction • synaptic transmission • ion transmembrane transport • regulation of membrane potential • neurological system process • transmembrane transport • chloride transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55879	57249
Ensembl	ENSG00000268089	ENSMUSG00000031344
UniProt	Q9UN88	Q9JLF1
RefSeq (mRNA)	NM_018558	NM_001290435
RefSeq (protein)	NP_061028	NP_001277364
Location (UCSC)	Chr X: 152.64 – 152.66 Mb	Chr X: 72.83 – 72.84 Mb
PubMed search	[1]	[2]

Gamma-aminobutyric acid receptor subunit theta is a protein that in humans is encoded by theGABRQ gene. The protein encoded by this gene is a subunit of the GABAA receptor.

The θ subunit has highest sequence similarity with the β1 subunit. This subunit coassembles with:

• α2, β1, and γ1
• α3 and β1
• α3, β1, and ε.

External links

• GABRQ protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)