FG-8205

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FG-8205
FG-8205.svg
Systematic (IUPAC) name
7-chloro-5-methyl-3-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Identifiers
CAS Number 122384-14-9 N
PubChem CID: 129710
ChemSpider 114837 YesY
ChEMBL CHEMBL307202 YesY
Chemical data
Formula C17H16ClN5O2
Molecular mass 357.794 g/mol
  • Clc4cccc3n2cnc(c1nc(on1)C(C)C)c2CN(C(=O)c34)C
  • InChI=1S/C17H16ClN5O2/c1-9(2)16-20-15(21-25-16)14-12-7-22(3)17(24)13-10(18)5-4-6-11(13)23(12)8-19-14/h4-6,8-9H,7H2,1-3H3 YesY
  • Key:SEWXZWMBVGJJPG-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

FG-8205[1] (L-663,581) is an imidazobenzodiazepine derivative related to bretazenil, which acts as a partial agonist at GABAA receptors, with slight selectivity for the α1-containing subtype. In animal tests it has anxiolytic and anticonvulsant effects but with little sedation or ataxia produced.[2][3][4][5]

See also

References

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