EEF1D
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Elongation factor 1-delta is a protein that in humans is encoded by the EEF1D gene.[1]
Function
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants have been found for this gene, however, the full length nature of only two variants has been determined.[2]
Interactions
EEF1D has been shown to interact with Glycyl-tRNA synthetase,[3] EEF1G[4][5] and KTN1,[6] and is predicted to interact with TMEM63A.[7]
References
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Further reading
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