ECT2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Protein ECT2 is a protein that in humans is encoded by the ECT2 gene.[1][2][3]

Function

The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.[3]

Interactions

ECT2 has been shown to interact with PARD6A.[4]

References

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Further reading

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