Cyclopenthiazide
From Infogalactic: the planetary knowledge core
File:Cyclopenthiazide.png | |
Systematic (IUPAC) name | |
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6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
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Clinical data | |
AHFS/Drugs.com | International Drug Names |
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Identifiers | |
CAS Number | 742-20-1 |
ATC code | C03AA07 (WHO) |
PubChem | CID: 2904 |
IUPHAR/BPS | 7899 |
ChemSpider | 2801 |
UNII | VX4S2N85F5 |
KEGG | D02061 |
ChEMBL | CHEMBL1373254 |
Chemical data | |
Formula | C13H18ClN3O4S2 |
Molecular mass | 379.88 g/mol |
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Cyclopenthiazide (trade name Navidrex) is a thiazide diuretic used in the treatment of heart failure and hypertension.
Synthesis
Contraindications
Thiazide diuretics increase the excretion of sodium and potassium ions and decrease the excretion of calcium ions and uric acid so they are contraindicated in patients with hyponatraemia, hypokalaemia, hypercalcaemia and hyperuricaemia. They are also contraindicated in patients with Addison's disease.
See also
References
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