Aildenafil

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Aildenafil
Aildenafil.svg
Names
IUPAC name
5-(5-(((3R,5S)-3,5-Dimethylpiperazin-1-yl)sulfonyl)-2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(4H)-one
Other names
Methisosildenafil
Identifiers
496835-35-9 YesY
ChemSpider 8316620 YesY
Jmol 3D model Interactive image
PubChem 16721107
  • InChI=1S/C23H32N6O4S/c1-6-8-18-20-21(28(5)27-18)23(30)26-22(25-20)17-11-16(9-10-19(17)33-7-2)34(31,32)29-12-14(3)24-15(4)13-29/h9-11,14-15,24H,6-8,12-13H2,1-5H3,(H,25,26,30)/t14-,15+ YesY
    Key: NFSWSZIPXJAYLR-GASCZTMLSA-N YesY
  • O=S(=O)(c3cc(C\1=N\C(=O)c2c(N/1)c(nn2C)CCC)c(OCC)cc3)N4C[C@H](N[C@@H](C)C4)C
Properties
C23H32N6O4S
Molar mass 488.61 g·mol−1
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

Aildenafil (methisosildenafil) is a synthetic chemical compound that is a structural analog of sildenafil (Viagra).[1] It was first reported in 2003,[2] and it is not approved by any health regulation agency. Like sildenafil, aildenafil is a phosphodiesterase type 5 inhibitor.

Aildenafil has been found as an adulterant in a variety of supplements which are sold as "natural" or "herbal" sexual enhancement products.[3][4][5][6][7] The United States Food and Drug Administration has warned consumers that any sexual enhancement product that claims to work as well as prescription products is likely to contain such a contaminant.[8]

See also

References

  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. Liu, Baoshun. Preparation of pyrazolopyrimidine derivatives for treatment of impotence. WO 2003016313 
  3. Lua error in package.lua at line 80: module 'strict' not found.
  4. Lua error in package.lua at line 80: module 'strict' not found.
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  7. Enforcement Report for June 30, 2010, United States Food and Drug Administration
  8. Hidden Risks of Erectile Dysfunction "Treatments" Sold Online, United States Food and Drug Administration, February 21, 2009