Ulobetasol

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Ulobetasol
Ulobetasol.png
Systematic (IUPAC) name
(6α,11β,16β)-21-chloro-6,9-difluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a601060
Identifiers
CAS Number 98651-66-2 N
ATC code D07AC21 (WHO)
PubChem CID: 5311167
ChemSpider 4470691 YesY
UNII 9P6159HM7T YesY
KEGG D08660 YesY
ChEMBL CHEMBL1201360 N
Synonyms (6S,8S,9S,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Chemical data
Formula C22H27ClF2O4
Molecular mass 428.897
  • ClCC(=O)[C@]3(O)[C@]2(C[C@H](O)[C@]4(F)[C@@]/1(\C(=C/C(=O)\C=C\1)[C@@H](F)C[C@H]4[C@@H]2C[C@@H]3C)C)C
  • InChI=1S/C22H27ClF2O4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1 YesY
  • Key:LEHFPXVYPMWYQD-XHIJKXOTSA-N YesY
 NYesY (what is this?)  (verify)

Ulobetasol (INN) or halobetasol (USAN) is a corticosteroid used to treat psoriasis. It is a group I corticosteroid under the US classification, the most potent class of such drugs. Halobetasol propionate is usually supplied as a 0.05% topical cream.

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