Aspartoacylase
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(Redirected from ASPA (gene))
| aspartoacylase (Canavan disease) | |
|---|---|
| Identifiers | |
| Symbol | ASPA |
| Entrez | 443 |
| HUGO | 756 |
| OMIM | 608034 |
| RefSeq | NM_000049 |
| UniProt | P45381 |
| Other data | |
| EC number | 3.5.1.15 |
| Locus | Chr. 17 p13-ter |
| aspartoacylase (aminocyclase) 3 | |
|---|---|
| Identifiers | |
| Symbol | ACY3 |
| Entrez | 91703 |
| HUGO | 24104 |
| RefSeq | NM_080658 |
| UniProt | Q96HD9 |
| Other data | |
| Locus | Chr. 11 q13 |
Aspartoacylase (EC 3.5.1.15, aminoacylase II, N-acetylaspartate amidohydrolase, acetyl-aspartic deaminase, acylase II) is a hydrolase enzyme with system name N-acyl-L-aspartate amidohydrolase.,[1][2] which breaks down N-acetylaspartate. A deficiency is associated with Canavan disease.This enzyme catalyses the following chemical reaction
- N-acyl-L-aspartate + H2O
a carboxylate + L-aspartate
References
External links
- aspartoacylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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